RT Book, Section
A1 Farivar, Alexander S.
A1 Vallières, Eric
A2 Sugarbaker, David J.
A2 Bueno, Raphael
A2 Colson, Yolonda L.
A2 Jaklitsch, Michael T.
A2 Krasna, Mark J.
A2 Mentzer, Steven J.
A2 Williams, Marcia
A2 Adams, Ann
SR Print(0)
ID 1105847385
T1 Resection of Substernal Goiter
T2 Adult Chest Surgery, 2e
YR 2015
FD 2015
PB McGraw-Hill Education
PP New York, NY
SN 978-0-07-178189-3
LK accesssurgery.mhmedical.com/content.aspx?aid=1105847385
RD 2024/04/16
AB Goiter  refers  to  an  enlargement  of  the  thyroid  gland.  The  condition  is  estimated  to  affect  5%  of  the  general  population.  While  the  definition  of  substernal  goiter  varies  in  the  medical  literature,  goiters  usually  are  considered  substernal  (also  referred  to  as  mediastinal,  intrathoracic,  or  retrosternal)  when  more  than  50%  of  the  thyroid  parenchyma  is  located  below  the  sternal  notch.  Such  tumors  have  been  a  focus  of  interest  for  surgeons  for  over  150  years.  Klein  is  credited  with  being  the  first  to  successfully  remove  a  mediastinal  goiter  in  1820,  although  the  earliest  surgical  description  of  mediastinal  thyroid  extension  dates  back  to  Haller  in  1749.  Today,  substernal  goiters  are  treated  by  a  number  of  different  surgical  specialists,  including  thoracic,  general,  and  head  and  neck  surgeons.  Goiters  account  for  as  many  as  10%  to  15%  of  space-occupying  mediastinal  lesions  and  are  the  most  common  of  the  superior  mediastinal  masses.