RT Book, Section A1 Su, Stacey A1 Colson, Yolonda L. A2 Sugarbaker, David J. A2 Bueno, Raphael A2 Colson, Yolonda L. A2 Jaklitsch, Michael T. A2 Krasna, Mark J. A2 Mentzer, Steven J. A2 Williams, Marcia A2 Adams, Ann SR Print(0) ID 1105847277 T1 Overview of Benign and Malignant Mediastinal Diseases T2 Adult Chest Surgery, 2e YR 2015 FD 2015 PB McGraw-Hill Education PP New York, NY SN 978-0-07-178189-3 LK accesssurgery.mhmedical.com/content.aspx?aid=1105847277 RD 2024/04/23 AB The mediastinum is defined as the space between the lungs. It is bordered by the sternum anteriorly, the thoracic inlet superiorly, the diaphragm inferiorly, and the ribs (Fig. 155-1). Mediastinal masses arise from structures that normally reside in the mediastinum, as well as those that migrate through it during development. The mediastinum is compartmentalized into four major spaces based on anatomic landmarks. The superior mediastinum extends from the thoracic inlet to an imaginary line between the angle of Louis and the fourth thoracic vertebral body. The anterior mediastinum spans the back of the sternum to the front of the ascending aorta and pericardium. The posterior mediastinum is located between the posterior pericardium and the spine; this includes the costovertebral sulci. The middle mediastinum lies between the anterior and posterior mediastinal compartments. These divisions are not precise and become less defined as lesions invade or displace adjacent organs, leading to distorted anatomy. Nevertheless, they provide a framework to classify and understand mediastinal diseases. With knowledge of the patient's age, location of the lesion, and presence or absence of sentinel signs and symptoms, a reasonable preoperative diagnosis often can be made.