RT Book, Section A1 Richards, William G. A2 Sugarbaker, David J. A2 Bueno, Raphael A2 Colson, Yolonda L. A2 Jaklitsch, Michael T. A2 Krasna, Mark J. A2 Mentzer, Steven J. A2 Williams, Marcia A2 Adams, Ann SR Print(0) ID 1105845048 T1 Mesothelioma Staging T2 Adult Chest Surgery, 2e YR 2015 FD 2015 PB McGraw-Hill Education PP New York, NY SN 978-0-07-178189-3 LK accesssurgery.mhmedical.com/content.aspx?aid=1105845048 RD 2024/04/23 AB Cancer staging systems are intended to assist clinicians to categorize patients diagnosed with a particular malignancy in terms of their life expectancy and potential response to specific therapeutic strategies. Generally speaking, patients categorized as early stage have anatomically localized malignancy associated with a longer life expectancy and better response particularly to local therapies directed at the primary tumor mass. Late stage patients are presumed to have metastatic disease indirectly disseminated to distant anatomical sites associated with shorter life expectancy and requiring systemic therapeutic approaches. A staging system is a set of criteria that defines such categories for a specific malignancy. Stage categories are defined in anatomical terms: How large is the tumor and what anatomical structures have become involved with (i.e., contain invasive proliferations of) tumor cells?