RT Book, Section A1 Issa, Nicolas C. A1 Baden, Lindsey R. A2 Sugarbaker, David J. A2 Bueno, Raphael A2 Colson, Yolonda L. A2 Jaklitsch, Michael T. A2 Krasna, Mark J. A2 Mentzer, Steven J. A2 Williams, Marcia A2 Adams, Ann SR Print(0) ID 1105844100 T1 Lung Infections and Interstitial Lung Disease: Overview and General Approach T2 Adult Chest Surgery, 2e YR 2015 FD 2015 PB McGraw-Hill Education PP New York, NY SN 978-0-07-178189-3 LK accesssurgery.mhmedical.com/content.aspx?aid=1105844100 RD 2024/04/19 AB The respiratory tract (Fig. 102-1) is in constant contact with the environment and exposed to direct inoculation by infectious and noninfectious agents. To defend itself against these agents, the respiratory tract is equipped with several types of defense mechanisms including both mechanical and immune-mediated mechanisms. Large size airborne particles (>5 microns) are filtered by the nose and are trapped by the nasal cilia. Intermediate size (1–5 microns) particles are deposited in the trachea and bronchi, and small size particles (0.01–1 microns) and infectious agents often are deposited in the bronchioles and the alveolar space (Fig. 102-2).