RT Book, Section A1 Hennon, Mark W. A1 Nwogu, Chumy E. A2 Sugarbaker, David J. A2 Bueno, Raphael A2 Colson, Yolonda L. A2 Jaklitsch, Michael T. A2 Krasna, Mark J. A2 Mentzer, Steven J. A2 Williams, Marcia A2 Adams, Ann SR Print(0) ID 1105843551 T1 Benign Lung Masses T2 Adult Chest Surgery, 2e YR 2015 FD 2015 PB McGraw-Hill Education PP New York, NY SN 978-0-07-178189-3 LK accesssurgery.mhmedical.com/content.aspx?aid=1105843551 RD 2024/09/09 AB Benign lung masses comprise a heterogeneous group of tumors that are defined by their lack of malignant features histologically and their nonaggressive clinical behavior. This is evidenced by the absence of invasion into surrounding tissue planes or metastatic spread to other structures. In a classic study, Martini1, who investigated the Memorial Sloan Kettering experience, demonstrated that less than 1% of resected lung lesions are benign. More recent reports have shown that despite advances in preoperative imaging and assessment, up to 9% of nodules suspected of being malignant prior to resection are found to be benign.2 Increasing utilization of CT scanning for lung cancer screening as well as for other cardiopulmonary diagnostic purposes has led to an increase in the number of patients being identified with pulmonary nodules. Given the overall low incidence of these tumors, differentiating a benign from a malignant lung mass can sometimes be difficult. Using a combination of clinical tools including a detailed history and physical examination, laboratory workup, radiographic imaging, and tissue sampling techniques, it is often possible to achieve an accurate assessment of a benign lung mass. It is this evaluation and correct characterization of an indeterminate pulmonary nodule that is invaluable in guiding treatment planning as well as assessing the overall prognosis of the patient.