RT Book, Section A1 Rice, Thomas W. A2 Sugarbaker, David J. A2 Bueno, Raphael A2 Colson, Yolonda L. A2 Jaklitsch, Michael T. A2 Krasna, Mark J. A2 Mentzer, Steven J. A2 Williams, Marcia A2 Adams, Ann SR Print(0) ID 1105841806 T1 Cancers of the Upper Aerodigestive Tract: Cervical Exenteration T2 Adult Chest Surgery, 2e YR 2015 FD 2015 PB McGraw-Hill Education PP New York, NY SN 978-0-07-178189-3 LK accesssurgery.mhmedical.com/content.aspx?aid=1105841806 RD 2024/10/16 AB Rarely, locally extensive but nonmetastatic cancers of the upper aerodigestive tract require resection. Cancers of the larynx, cervical trachea, hypopharynx, cervical esophagus, and thyroid can be exenterated with a pharyngo-laryngo-tracheo-esophagectomy as primary therapy, salvage after failed primary therapy, treatment of locally recurrent cancer, treatment of benign complications of successful primary therapy, or long-term palliation. The enormity of these procedures is further overshadowed by the likely possibility of limited survival, the potential for significant complications, and the expected negative impact upon quality of life. However, in curatively resected and properly reconstructed patients, long-lasting effects are little more than that experienced by the laryngectomy patient.