RT Book, Section A1 Johnston, Peter V. A1 Gerstenblith, Gary A2 Yuh, David D. A2 Vricella, Luca A. A2 Yang, Stephen C. A2 Doty, John R. SR Print(0) ID 1104593900 T1 Stem Cells for Cardiac Surgical Disease T2 Johns Hopkins Textbook of Cardiothoracic Surgery YR 2014 FD 2014 PB McGraw-Hill Education PP New York, NY SN 978-0-07-166350-2 LK accesssurgery.mhmedical.com/content.aspx?aid=1104593900 RD 2024/10/03 AB There are an estimated 5.8 million people in the United States with heart failure.1Stem cell therapy for the heart represents a novel method by which dysfunctional cardiac tissue might be repaired or replaced, thereby alleviating heart failure and decreasing or eliminating life-threatening arrhythmias.Potential sources of stem cell therapy for the heart include the bone marrow, circulating progenitor cells, embryonic stem cells, and the heart itself.Multiple modalities exist for delivery of stem cell therapy to the heart, including traditional and minimally invasive surgical methods as well as intravenous and percutaneous catheter-based techniques.