RT Book, Section
A1 Tiao, Greg M.
A2 Ziegler, Moritz M.
A2 Azizkhan, Richard G.
A2 Allmen, Daniel von
A2 Weber, Thomas R.
SR Print(0)
ID 1100440171
T1 Liver Transplantation
T2 Operative Pediatric Surgery, 2e
YR 2014
FD 2014
PB McGraw-Hill Education
PP New York, NY
SN 978-0-07-162723-8
LK accesssurgery.mhmedical.com/content.aspx?aid=1100440171
RD 2024/04/16
AB Though  liver  transplantation  remains  a  technically  challenging  operative  procedure  and  patients  are  complex  in  their  perioperative  management,  the  use  of  whole  organ,  reduced  size,  split  liver,  and  even  living  donors  has  resulted  in  an  overall  improved  patient  survival  approaching  90%  for  infants  and  children  alike.  These  techniques  have  also  reduced  waiting  list  mortality.The  indications  for  liver  transplantation  have  become  somewhat  more  liberal  and  have  improved  outcomes  for  children  with  hepatoblastoma,  a  pediatric  disease  with  a  here-to-fore  dismal  prognosis.Improved  immunosuppression  includes  multiple  drugs  and  in  some  centers  even  steroid-free  immunosuppression.  These  protocols  have  limited  the  adverse  impact  of  allograft  rejection  while  minimizing  the  complications  of  immunosuppression  including  infection  and  PTLD.  Chronic  rejection  awaits  a  better  solution.