RT Book, Section A1 Banever, Gregory T. A2 Ziegler, Moritz M. A2 Azizkhan, Richard G. A2 Allmen, Daniel von A2 Weber, Thomas R. SR Print(0) ID 1100431863 T1 Transfusion Medicine and Coagulation Disorders T2 Operative Pediatric Surgery, 2e YR 2014 FD 2014 PB McGraw-Hill Education PP New York, NY SN 978-0-07-162723-8 LK accesssurgery.mhmedical.com/content.aspx?aid=1100431863 RD 2024/04/24 AB Typical transfusion thresholds include a hematocrit of 21% in asymptomatic patients, and 30% in critically ill premature neonates or patients undergoing major surgery.Patients with sickle cell disease (SCD) require strict physiologic optimization preoperatively, and close monitoring after surgery, to prevent complications.A platelet count of 50,000/mm3 is adequate for procedures such as central line placement.For massive transfusion, a blood component ratio of 1:1:1 for red blood cells (RBCs): fresh frozen plasma (FFP): platelets is recommended.Most transfusion reactions typically fall into one of 3 categories: hemolytic, febrile, and urticarial.