RT Book, Section
A1 Doherty, Gerard M.
SR Print(0)
ID 58102459
T1 Thoracic Aortic Dissection
T2 Quick Answers Surgery
YR 2010
FD 2010
PB The McGraw-Hill Companies
PP New York, NY
SN 
LK accesssurgery.mhmedical.com/content.aspx?aid=58102459
RD 2024/04/24
AB •  Often  lethal  event•  Degeneration  of  aortic  media  is  hallmark  of  disease•  Pathogenesis  controversial  1.  Medial  degeneration  leads  to  rupture  of  vasa  vasorum2.  Intimal  tears  allows  blood  to  shear  weakened  media•  Location  of  intimal  tear:  Ascending  aorta,  62%;  arch,  10%;  isthmus,  16%;  rest  in  distal  aorta•  Risk  factors  include:  -Hypertension-Atherosclerosis-Iatrogenic  injury  (catheter  or  open  heart  surgery)-Closed  chest  trauma-Marfan  syndrome-Aortic  coarctation