RT Book, Section A1 Doherty, Gerard M. SR Print(0) ID 58101781 T1 Splenic Neoplasms T2 Quick Answers Surgery YR 2010 FD 2010 PB The McGraw-Hill Companies PP New York, NY SN LK accesssurgery.mhmedical.com/content.aspx?aid=58101781 RD 2024/04/23 AB • Splenic involvement (splenomegaly and hypersplenism) due to infiltration of lymphocytes or mast cells or initiation of extramedullary hematopeosis• Splenomegaly and hypersplenism, resulting in anemia, thrombocytopenia, and/or neutropenia• Splenectomy may be indicated for hypersplenism, for diagnosis, or for primary surgical removal of the predominant or only site of disease