RT Book, Section
A1 Doherty, Gerard M.
SR Print(0)
ID 58098425
T1 Porphyria, Acute
T2 Quick Answers Surgery
YR 2010
FD 2010
PB The McGraw-Hill Companies
PP New York, NY
SN 
LK accesssurgery.mhmedical.com/content.aspx?aid=58098425
RD 2024/04/23
AB •  Acute  porphyrias  are  a  group  of  inherited  diseased  that  arise  from  errors  in  heme  biosynthesis  leading  to  overproduction  of  a  porphyrin  species•  Acute  intermittent  porphyria  has  the  most  serious  consequences  and  is  the  form  in  which  patients  commonly  manifest  an  acute  abdomen•  Classic  patient  is  a  young  woman  (teens  to  early  20s)  with  an  unexplained  abdominal  crisis•  Abdominal  symptoms  are  thought  to  be  due  to  acute  (abdominal  visceral)  autonomic  dysfunction•  Acute  peripheral  or  CNS  dysfunction•  Recurrent  psychiatric  illnesses•  Hyponatremia•  Porphobilinogen  in  the  urine  during  acute  attacks