RT Book, Section A1 Doherty, Gerard M. SR Print(0) ID 58095876 T1 Paget Disease T2 Quick Answers Surgery YR 2010 FD 2010 PB The McGraw-Hill Companies PP New York, NY SN LK accesssurgery.mhmedical.com/content.aspx?aid=58095876 RD 2024/04/25 AB • Also known as osteitis deformans• Nonmalignant disease involving accelerated bone resumption followed by deposition of dense, disorganized, and ineffectively mineralized bone matrix• Etiology is unknown, although posited to be infectious; hereditary causes possible as well• 3 phases of disease: -Intense bone resorption-Production of abundant woven bone with ineffective mineralization-Deposition of sclerotic, chaotic cortical and trabecular bone