RT Book, Section A1 Doherty, Gerard M. SR Print(0) ID 58095544 T1 Neuroblastoma T2 Quick Answers Surgery YR 2010 FD 2010 PB The McGraw-Hill Companies PP New York, NY SN LK accesssurgery.mhmedical.com/content.aspx?aid=58095544 RD 2024/09/10 AB • Most common extracranial solid tumor and most common abdominal solid malignancy in children• Associated with the following:-Neurofibromatosis type I-Beckwith-Wiedemann syndrome-Hirschsprung disease-Musculoskeletal and cardiovascular malformation-Turner syndrome• Factors that place patient at high risk include: -Age > 1 year-Stage 3 and 4-Unfavorable Shimada classification (histology)-N-myc amplification-No trk expression-Diploid-1p deletion-> 142 ferritin ng/mL-> 1500 LDH IU/L