RT Book, Section
A1 Doherty, Gerard M.
SR Print(0)
ID 58094558
T1 Melanoma
T2 Quick Answers Surgery
YR 2010
FD 2010
PB The McGraw-Hill Companies
PP New York, NY
SN 
LK accesssurgery.mhmedical.com/content.aspx?aid=58094558
RD 2024/04/25
AB •  Predominately  a  disease  of  fair-skinned  people•  Only  15%  of  melanomas  develop  in  preexisting  nevi,  the  remainder  arise  de  novo•  Most  important  prognostic  factors  include:  -Vertical  height  of  melanoma-Sentinel  lymph  node  status-Number  of  positive  lymph  nodes-Presence  of  metastatic  disease•  Melanoma  typically  metastasizes  by  the  lymphatic  route  in  a  predictable  and  orderly  fashion•  4  histologic  categories  of  melanoma:-Superficial  spreading,  70%  of  cases-Nodular  melanoma,  15%  of  cases-Lentigo  maligna  melanoma,  4-10%  of  cases-Acral  lentiginous  melanoma,  2-8%  of  cases•  Melanoma  most  commonly  metastasizes  to  the  lungs,  liver,  and  brain  but  can  also  involve  the  bone,  adrenals,  heart,  and  bowel