RT Book, Section
A1 Doherty, Gerard M.
SR Print(0)
ID 58093315
T1 Atrioventricular Canal Defect
T2 Quick Answers Surgery
YR 2010
FD 2010
PB The McGraw-Hill Companies
PP New York, NY
SN 
LK accesssurgery.mhmedical.com/content.aspx?aid=58093315
RD 2024/04/25
AB •  A  congenital  heart  lesion  that  increases  pulmonary  artery  (PA)  blood  flow•  Causes  left  to  right  shunt,  results  in  lung  infection,  pulmonary  vascular  congestion,  PA  hypertension,  right  heart  failure,  pulmonary  vasoconstriction,  pulmonary  vascular  obstructive  disease•  Eisenmenger  syndrome:  Increased  pulmonary  hypertension  to  such  extent  that  left  to  right  shunt  ceases  and  shunt  becomes  right  to  left,  requiring  heart-lung  transplant•  Inhaled  nitric  oxide,  oxygen,  or  IV  tolazoline  reverses  PA  vasoconstriction•  PA  band  is  palliative  and  can  reduce  PA  flow  to  alleviate  RV  failure  and  progression  of  pulmonary  hypertension•  Deficiency  of  tissue  in  central  region  of  heart  (lower  atrial  septum-septum  primum,  mitral  valve,  tricuspid  valve)•  Defect  in  endocardial  and  conal  tissue  development•  Range  of  defects  possible•  Partial  AV  canal  defect:  Septum  primum  atrial  septal  defect  (ASD),  deficient  lower  atrial  septum  only•  Transitional  AV  canal  defect:  Intermediate  form  with  ASD  and  minor  deficiency  in  upper  ventricular  system•  Complete  AV  canal  defect:  ASD  and  severe  valve  anomalies•  Associated  with  left  superior  vena  cava  (SVC),  additional  ventricular  septal  defect  (VSD),  anomalous  pulmonary  venous  connection,  patent  ductus  arteriosus  (PDA),  tetralogy  of  Fallot