RT Book, Section A1 Doherty, Gerard M. SR Print(0) ID 58092561 T1 Aortic Valve Regurgitation T2 Quick Answers Surgery YR 2010 FD 2010 PB The McGraw-Hill Companies PP New York, NY SN LK accesssurgery.mhmedical.com/content.aspx?aid=58092561 RD 2024/04/16 AB • Aortic valve (AV): Usually tricuspid, composed of fibrous skeleton, 3 cusps, and sinuses of Valsalva• Free edge of each cusp is concave and thicker, with fibrous node at midpoint• During systole: Eddy currents in sinuses of Valsalva prevent occlusion of coronary ostia• During diastole: Cusps fall closed and coapt, supports ejected column of blood• Coronary arteries arise from 2 of 3 sinuses of Valsalva• Aortic regurgitation (AR) is caused by abnormal coaptation of valve leaflets, allowing blood to return from aorta to ventricle during diastole• Etiology of chronic AR: -Rheumatic dilation-Annuloaortic ectasia-Cystic medial necrosis-Atherosclerosis-Syphilis-Arthritic inflammatory disease-Congenital bicuspid valve• Etiology of acute AR: -Endocarditis-Acute aortic dissection-Trauma• LV becomes eccentrically hypertrophied and dilated