RT Book, Section
A1 Cooperberg, Matthew R.
A1 Presti, Joseph C.
A1 Shinohara, Katsuto
A1 Carroll, Peter R.
A2 McAninch, Jack W.
A2 Lue, Tom F.
SR Print(0)
ID 56945773
T1 Chapter 23. Neoplasms of the Prostate Gland
T2 Smith & Tanagho's General Urology, 18e
YR 2013
FD 2013
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-162497-8
LK accesssurgery.mhmedical.com/content.aspx?aid=56945773
RD 2024/04/20
AB The  prostate  gland  is  the  male  organ  most  commonly  afflicted  with  either  benign  or  malignant  neoplasms.  McNeal  et  al  (1988)  popularized  the  concept  of  zonal  anatomy  of  the  prostate.  Three  distinct  zones  have  been  identified  (Figure  23–1).  The  peripheral  zone  accounts  for  70%  of  the  volume  of  the  young  adult  prostate,  the  central  zone  accounts  for  25%,  and  the  transition  zone  accounts  for  5%.  These  anatomic  zones  have  distinct  ductal  systems  but,  more  important,  are  differentially  afflicted  with  neoplastic  processes.  Sixty  to  seventy  percent  of  carcinomas  of  the  prostate  (CaP)  originate  in  the  peripheral  zone,  10–20%  in  the  transition  zone,  and  5–10%  in  the  central  zone  (McNeal  et  al,  1988).  Benign  prostatic  hyperplasia  (BPH)  uniformly  originates  in  the  transition  zone  (Figure  23–2).