RT Book, Section A1 Tanagho, Emil A. A1 Nguyen, Hiep T. A2 McAninch, Jack W. A2 Lue, Tom F. SR Print(0) ID 56942594 T1 Chapter 13. Vesicoureteral Reflux T2 Smith & Tanagho's General Urology, 18e YR 2013 FD 2013 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-162497-8 LK accesssurgery.mhmedical.com/content.aspx?aid=56942594 RD 2024/10/04 AB Under normal circumstances, the ureterovesical junction allows urine to enter the bladder but prevents urine from regurgitating into the ureter, particularly at the time of voiding. In this way, the kidney is protected from high pressure in the bladder and from contamination by infected vesical urine. When this valve is incompetent, the chance for development of urinary infection is significantly enhanced, and pyelonephritis may occur. In significant cases especially in children, pyelonephritis—acute, chronic, or healed—is secondary to vesicoureteral reflux (VUR).