RT Book, Section
A1 Porterfield, John R.
A1 Thompson, Geoffrey B.
A2 Morita, Shane Y.
A2 Dackiw, Alan P. B.
A2 Zeiger, Martha A.
SR Print(0)
ID 6163237
T1 Chapter 14. Hypercortisolism
T2 McGraw-Hill Manual: Endocrine Surgery
YR 2010
FD 2010
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-160645-5
LK accesssurgery.mhmedical.com/content.aspx?aid=6163237
RD 2024/04/18
AB Hypercortisolism  is  a  disorder  characterized  by  excessive  circulating  cortisol  from  either  endogenous  or  exogenous  sources,  which  can  cause  detrimental  changes  to  nearly  every  organ  system.  Collectively,  the  ravages  of  hypercortisolism  are  best  classified  as  Cushing's  syndrome  (CS).  The  term  Cushing's  syndrome  is  used  for  all  causes  of  hypercortisolism,  and  the  term  Cushing's  disease  is  reserved  specifically  for  cases  of  pituitary-dependent  CS.  The  most  common  cause  of  CS  is  exogenous  administration  of  glucocorticoids,  which  are  used  for  their  beneficial  antiinflammatory,  antineoplastic,  and  immunosuppressive  effects.  This  chapter  focuses  solely  on  endogenous  CS  and  is  a  summary  of  our  recent  review  at  the  Mayo  Clinic  in  Rochester,  Minnesota.1