RT Book, Section A1 Amara, Shamly Dhiman A1 Inabnet, William B. A2 Morita, Shane Y. A2 Dackiw, Alan P. B. A2 Zeiger, Martha A. SR Print(0) ID 6163181 T1 Chapter 13. Hyperaldosteronism T2 McGraw-Hill Manual: Endocrine Surgery YR 2010 FD 2010 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-160645-5 LK accesssurgery.mhmedical.com/content.aspx?aid=6163181 RD 2024/10/14 AB Hyperaldosteronism is caused by the hypersecretion of the hormone aldosterone by the adrenal cortex, leading to the clinical syndrome of hypertension and hypokalemia. This syndrome was originally described by Conn in 1955 and thus is often referred to as Conn's syndrome.1 In approximately 50% to 60% of cases, hyperaldosteronism is caused by a solitary adrenal nodule or "aldosteronoma." The remainder of cases (~30% to 40%) are caused by bilateral adrenal hyperplasia.2 Unilateral adrenal hyperplasia and aldosterone-producing ovarian tumor may also cause hyperaldosteronism.