RT Book, Section A1 Méndez, Jane E. A1 Singletary, S. Eva A1 Babiera, Gildy V. A2 Kuerer, Henry M. SR Print(0) ID 6415594 T1 Chapter 72. Surgery in Patients with Stage IV Metastatic Breast Cancer T2 Kuerer's Breast Surgical Oncology YR 2010 FD 2010 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-160178-8 LK accesssurgery.mhmedical.com/content.aspx?aid=6415594 RD 2024/04/24 AB Historically, women who present with stage IV metastatic breast cancer (MBC), even those with an intact primary tumor, are not offered surgical treatment. Instead, the recommended primary treatment approach is systemic therapy. However, improved breast cancer screening and imaging technology have presented a different dilemma: patients with MBC may have oligometastatic or stable metastatic disease with an operable intact primary tumor, suggesting that surgery may be effective. Furthermore, over the past 25 years, multimodality treatments for new and advanced breast cancers have resulted in improved median survival times for patients with MBC.1 Therefore, for patients with MBC, it is time to reevaluate the role of resection of the intact primary tumor and the role of metastasectomy in patients without an intact primary tumor.