RT Book, Section A1 Fine, Richard E. A2 Kuerer, Henry M. SR Print(0) ID 6413937 T1 Chapter 56. Mammographic and Intraoperative Ultrasound Guidance T2 Kuerer's Breast Surgical Oncology YR 2010 FD 2010 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-160178-8 LK accesssurgery.mhmedical.com/content.aspx?aid=6413937 RD 2024/03/29 AB An increasing number of nonpalpable breast lesions are identified due to screening mammography and breast magnetic resonance imaging (MRI). After appropriate diagnostic imaging workup, many of these image-detected abnormalities require a biopsy for pathologic confirmation. The positive predictive value of mammography (the number of cancers diagnosed per number of biopsies recommended) historically has ranged from 15% to 35%.1 Fortunately, a substantial number of these lesions are initially evaluated with percutaneous image-guided breast biopsy, providing a less costly, less invasive method to obtain an accurate diagnosis without sacrificing accuracy. After a benign diagnosis is obtained with a minimally invasive image-guided biopsy, no further workup is recommended, and the patient is placed in an established follow-up protocol. The goal of reserving open surgical biopsy for definitive clinical management and eliminating it for the sole purpose of diagnosis is increasingly being accomplished.