RT Book, Section A1 Smart, Chanel E. A1 Smart, Chanel E. A1 Furnival, Colin M. A1 Furnival, Colin M. A1 Lakhani, Sunil R. A1 Lakhani, Sunil R. A2 Kuerer, Henry M. SR Print(0) ID 6408548 T1 Chapter 17. High-Risk Lesions: ALH/LCIS/ADH T2 Kuerer's Breast Surgical Oncology YR 2010 FD 2010 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-160178-8 LK accesssurgery.mhmedical.com/content.aspx?aid=6408548 RD 2024/09/07 AB The multistep model for breast carcinogenesis suggests that invasive carcinomas arise from preinvasive "hyperplastic" and neoplastic proliferations. These early proliferative lesions have taken on greater significance as a result of the mammographic screening and detection programs. Pathologists are encountering these proliferative lesions with increasing frequency, and this has highlighted deficiencies in classification systems as well as a lack of data on natural history, making clinical management a challenge.