RT Book, Section A1 Soran, Atilla A1 Vogel, Victor G. A2 Kuerer, Henry M. SR Print(0) ID 6406333 T1 Chapter 10. Chemoprevention in the Clinical Setting T2 Kuerer's Breast Surgical Oncology YR 2010 FD 2010 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-160178-8 LK accesssurgery.mhmedical.com/content.aspx?aid=6406333 RD 2024/04/19 AB Breast cancer is a complex disease, resulting from the interaction of nonmodifiable factors such as an individual's genome, age at menarche, menopause, and family history; along with modifiable risk factors such as environmental, hormonal, and lifestyle factors The goal of preventing breast cancer is to identify high-risk individuals who would benefit most from preventive therapies such as chemoprevention and risk-reducing surgeries. Chemoprevention can be defined as the use of natural or synthetic chemical agents to reverse, suppress, or prevent carcinogenic progression to invasive cancer.1-5