RT Book, Section A1 Taylor, Bryce R. A2 Hall, Jesse B. A2 Schmidt, Gregory A. A2 Wood, Lawrence D.H. SR Print(0) ID 2296554 T1 Chapter 85. Acute Pancreatitis in the Critically Ill T2 Principles of Critical Care, 3e YR 2005 FD 2005 PB The McGraw-Hill Companies PP New York, NY SN 9780071416405 LK accesssurgery.mhmedical.com/content.aspx?aid=2296554 RD 2023/02/04 AB Hypoperfusion injury is the most important of many possible causes of pancreatitis in the ICU setting.Serial computed tomography is most useful in confirming the diagnosis and in following the inflammatory process.The likelihood of multisystem failure is high, and preventive measures must be instituted early.Initial treatment is supportive, with aggressive fluid and electrolyte replacement and close monitoring of hemodynamic, pulmonary, and renal status.Surgical intervention is indicated for deteriorating patients with a surgically correctable lesion and in patients with complications of the disease, such as major hemorrhage, abscess, or symptomatic pseudocyst.Close supervision by an experienced abdominal surgeon in collaboration with an intensivist is important in recognizing the indications for surgical exploration.