RT Book, Section
A1 Mack, Michael J.
A2 Cohn, Lawrence H.
SR Print(0)
ID 55924037
T1 Chapter 45. Percutaneous Catheter-Based Mitral Valve Repair
T2 Cardiac Surgery in the Adult, 4e
YR 2012
FD 2012
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-163310-9
LK accesssurgery.mhmedical.com/content.aspx?aid=55924037
RD 2024/04/19
AB There  has  been  intense  interest  over  the  past  decade  in  developing  percutaneous  catheter-based  techniques  to  manage  valvular  heart  disease.1–4  Although  the  success  has  been  rapid  to  the  point  of  being  disruptive  in  catheter  treatment  of  aortic  stenosis,  progress  has  been  much  more  modest  in  correcting  mitral  regurgitation  (MR)  percutaneously.5  The  success  of  catheter-based  treatment  of  aortic  stenosis  can  be  attributed  to  a  singular  pathophysiology  of  the  disease  and  the  successful  development  of  delivery  systems  and  techniques  to  treat  this  disorder  using  conventional  imaging  techniques.  The  field  of  percutaneous  mitral  valve  repair,  however,  has  not  progressed  nearly  as  rapidly  for  a  host  of  reasons.  These  include  the  complex  pathophysiology  of  MR  with  diverse  causes  as  well  as  challenging  imaging  and  complex  delivery  issues.  These  obstacles  have  led  to  slower  than  anticipated  clinical  adoption  of  catheter-based  approaches  for  the  treatment  of  MR.  To  understand  the  potential  for  successful  therapy,  it  is  first  instructive  to  examine  the  pathophysiology  of  the  various  mechanisms  of  the  disease.