RT Book, Section A1 Zerbib, Yoann A1 Brault, Clément A1 Slama, Michel A2 Schmidt, Gregory A. A2 Kress, John P. A2 Douglas, Ivor S. SR Print(0) ID 1201882095 T1 Takotsubo Syndrome T2 Hall, Schmidt and Wood’s Principles of Critical Care, 5th Edition YR 2023 FD 2023 PB McGraw Hill PP New York, NY SN 9781264264353 LK accesssurgery.mhmedical.com/content.aspx?aid=1201882095 RD 2024/10/10 AB KEY POINTSCatecholamine toxicity seems to be the key mechanism of takotsubo.Emotional or physical triggers are almost always present in the history of takotsubo.The dominant pattern is the apical ballooning form.Takotsubo is a diagnosis of exclusion: myocardial infarction and myocarditis should be ruled out, generally requiring coronary angiography. MRI may also be useful.Echocardiography is the main tool to diagnose, follow, and detect complications.Severe cardiac failure and cardiogenic shock are the main causes of ICU hospitalization.Left ventricular outflow tract obstruction is frequent in patients with takotsubo.Management is based in very little evidence: anticoagulants, beta-blockers (in case of obstruction), levosimendan, and mechanical hemodynamical support have been advocated.