RT Book, Section A1 Schrantz, Stephen A1 Czapar, Anna A1 Karmarkar, Ellora A1 Lew, Allison A1 MacKenzie, Erica A1 Petit, Natasha A2 Schmidt, Gregory A. A2 Kress, John P. A2 Douglas, Ivor S. SR Print(0) ID 1201805692 T1 Management of the Critically Ill Patient with HIV/AIDS T2 Hall, Schmidt and Wood’s Principles of Critical Care, 5th Edition YR 2023 FD 2023 PB McGraw Hill PP New York, NY SN 9781264264353 LK accesssurgery.mhmedical.com/content.aspx?aid=1201805692 RD 2024/10/14 AB KEY POINTSCombination antiretroviral therapy (cART) has been shown to prolong survival and disease-free interval. Interruption in adherence to treatment is a major risk for opportunistic infections (OIs) leading to critical care needs.Because of better treatment and prolonged survival, more patients are admitted to the ICU who have HIV/AIDS as an underlying illness as opposed to the cause of ICU admission.Assessment of immunologic functioning via measurement of CD4+ lymphocytes is fundamental in determining risk for OIs.Continuation or initiation of cART during the period of critical illness is dependent on the ability to tolerate treatment and presence or absence of certain OIs. Presence of an immune reconstitution inflammatory syndrome should often be considered.Proper diagnosis of OI is important to initiate prompt targeted treatment.Recognition of the social aspects of the patient’s care that lead to critical illness is important to reduce re-admissions and complications in the care of the patient.