RT Book, Section A1 Mouawad, Nicolas J. A1 Nasif, Abdullah A2 Nazzal, Munier A2 Blebea, John A2 Osman, Mohamed F. SR Print(0) ID 1200678093 T1 Acute Limb Ischemia T2 Vascular and Endovascular Surgery: Clinical Diagnosis and Management YR 2024 FD 2024 PB McGraw Hill PP New York, NY SN 9781260462715 LK accesssurgery.mhmedical.com/content.aspx?aid=1200678093 RD 2024/11/09 AB The history of the recognition and surgical treatment of lower limb ischemia dates back to the Middle Ages. The twin Saints Comas and Damian were ascribed to have saved a gangrenous limb in the thirteenth century and became patrons of future surgeons. The physicians who followed developed the theories of blood flow, anatomy of the arterial circulation, and recognition that occlusive disease was the cause of limb ischemia and gangrene. Innovative physicians developed the techniques of arterial surgery and bypass grafting to restore limb blood flow and allow the healing of lesions. In the 1960s, the era of endovascular intervention began through the pioneering work of Charles Dotter who developed techniques to image diseased arteries during a recanalization procedure. The development of guide wires, angioplasty balloons, and stents quickly followed. Management of lower limb ischemia and the diabetic foot will continue to evolve, building on the history and passion of preceding physicians and surgeons.1