RT Book, Section
A1 Bijol, Vanesa
A2 Molmenti, Ernesto Pompeo
SR Print(0)
ID 1194189371
T1 Polyomavirus Nephropathy
T2 Molmenti’s Kidney and Pancreas Transplantation: Operative Techniques and Medical Management, 2e
YR 2023
FD 2023
PB McGraw Hill
PP New York, NY
SN 9781260474275
LK accesssurgery.mhmedical.com/content.aspx?aid=1194189371
RD 2024/04/23
AB 69-year-old  man  status  post  deceased  donor  kidney  transplant  for  NSAIDs-related  chronic  tubulo-interstitial  disease  10  months  prior  to  current  presentation.  Azathioprine  had  to  be  discontinued  due  to  pancytopenia.  Corticosteroids  were  started.  A  biopsy  was  obtained  to  evaluate  an  elevated  creatinine  level.Biopsy  reveals  extensive  inflammation  with  frequent  tubulitis  (Figures  112-70  and  112-71).  Some  tubular  epithelial  cells  reveal  enlarged  nuclei  with  viral  inclusions.  SV40  polyomavirus  stain  is  positive  in  nuclei  of  infected  cells  by  immunoperoxidase  technique  (Figure  112-72).