RT Book, Section A1 Cagliani, Joaquin A A1 Kolwitz, Christine E A1 Montgomery, Robert A A2 Molmenti, Ernesto Pompeo SR Print(0) ID 1194180058 T1 HLA and ABO Desensitization T2 Molmenti’s Kidney and Pancreas Transplantation: Operative Techniques and Medical Management, 2e YR 2023 FD 2023 PB McGraw Hill PP New York, NY SN 9781260474275 LK accesssurgery.mhmedical.com/content.aspx?aid=1194180058 RD 2024/10/10 AB Highly polymorphic antigens expressed on the surface of cellsHave crucial roles in defense against foreign pathogens and in tumor immune surveillanceAntibodies against these antigens can develop as a result of pregnancy, transplantation, or blood transfusionHuman leukocyte antigen (HLA) sensitization adversely affects both access to and the outcomes of transplantationImproved identification of HLA molecules and of the specificity of HLA antibodies has improved transplant graft survivalDesensitization of anti-HLA antibodies is essential to enable meaningful progress in the field of transplantation and increase the likelihood that a patient will receive a transplant offer.