RT Book, Section A1 Patri, Pallavi A1 Muthukumar, Thangamani A2 Molmenti, Ernesto Pompeo SR Print(0) ID 1194179986 T1 Transplant Immunology T2 Molmenti’s Kidney and Pancreas Transplantation: Operative Techniques and Medical Management, 2e YR 2023 FD 2023 PB McGraw Hill PP New York, NY SN 9781260474275 LK accesssurgery.mhmedical.com/content.aspx?aid=1194179986 RD 2024/03/29 AB The major barrier to successful transplantation is the recipient’s immune response directed against the donor kidney. The transplanted kidney is recognized as foreign by the body’s immune system. This foreignness is mediated primarily by proteins encoded by the genes located in the major histocompatibility complex (MHC) region. The focus of this chapter is to outline the major immune processes of allograft recognition and response and the methods used to define the patient’s immune profile.