RT Book, Section A1 Molmenti, Ernesto Pompeo A1 de Santibañes, Martin A1 McCann-Molmenti, Alexia A1 Miyara, Santiago J. A1 Molmenti, Hebe A1 Sardo Molmenti, Christine L. A1 Cagliani, Joaquin A1 Sotiropoulos, Georgios C. A1 Radtke, Arnold A1 Sgourakis, Georgios A1 César Bassan, Pablo A1 Figari Bizzotto, Sabina A1 Morales, Luis Fernando A1 Nicastro, Jeffrey M. A1 Coppa, Gene F. A1 Rilo, Horacio A1 de Santibañes, Eduardo A2 Molmenti, Ernesto Pompeo A2 Santibañes, Martin de A2 Santibañes, Eduardo de SR Print(0) ID 1180113042 T1 Emergency Total Hepatectomy as a Bridge to Liver Transplantation T2 Liver Transplantation: Operative Techniques and Medical Management YR 2021 FD 2021 PB McGraw Hill PP New York, NY SN 9781260462517 LK accesssurgery.mhmedical.com/content.aspx?aid=1180113042 RD 2024/04/24 AB Highly unstable individuals with liver failure who:Are candidates for liver transplantationHave no immediately available liver grafts for transplantationHave severe physiologic derangementsUnresponsive to therapyEntirely attributable to their liver failureCauses of liver failure:Fulminant hepatic failure associated with massive necrosisAcute graft failure associated with massive necrosisPrimary graft nonfunctionMassive trauma with exsanguinationSpontaneous hepatic ruptureMassive uncontrolled hemorrhageOther“Toxic liver syndrome”Total liver necrosisCardiovascular shockRenal failureLikely respiratory failureNeed for:Vasopressor supportRenal replacement therapyMechanical ventilationThe decision to proceed with emergency total hepatectomy as the first of a 2-stage transplant procedure should take into consideration:High mortality associated with:Current conditionAnhepatic stateWhether total hepatectomy will bring enough stability to justify transplantationExtent and reversibility of multiorgan failurePresence of sepsisNeurologic statusIntensive medical management is required to maintain some stability during the anhepatic phase.In instances where a liver graft becomes available, it should be determined that the recipient is stable enough to tolerate the implantation.