RT Book, Section
A1 Diaz, Jose J.
A1 Collier, Bryan
A2 Feliciano, David V.
A2 Mattox, Kenneth L.
A2 Moore, Ernest E.
SR Print(0)
ID 1175136868
T1 Gastrointestinal Failure
T2 Trauma, 9e
YR 2020
FD 2020
PB McGraw Hill
PP New York, NY
SN 9781260143348
LK accesssurgery.mhmedical.com/content.aspx?aid=1175136868
RD 2024/04/20
AB KEY  POINTSIn  the  critically  ill  or  injured  patient,  gut  dysfunction  commonly  occurs  and  can  take  various  forms,  from  food  intolerance  to  life-threating  conditions  that  can  progress  to  multiple  organ  dysfunction  syndrome  (MODS)  or  persistent  inflammatory,  immunosuppressed,  catabolic  syndrome  (PICS).Gut  injury  can  be  described  as  an  ischemia/reperfusion  event  that  can  present  as  severe  as  nonocclusive  small  bowel  ischemia  to  the  abdominal  compartment  syndrome.More  commonly,  gastrointestinal  (GI)  dysfunction  will  manifest  as  gastroesophageal  reflux,  gastroparesis,  duodenogastric  ileus,  or  malabsorption  as  a  manifestation  of  food  intolerance.Recognition  of  the  human  microbiome  as  an  important  component  of  gut  health  and  the  alterations  in  the  microbiome  during  critical  illness  has  spurred  renewed  interest  in  the  microbiology  of  the  GI  tract.The  chapter  will  review  the  pathophysiology  and  the  current  best  practice  recommendations  for  medical  management.