RT Book, Section
A1 Andersson, Karl-Erik
A2 McAninch, Jack W.
A2 Lue, Tom F.
SR Print(0)
ID 1171184633
T1 Neurophysiology and Pharmacology of the Lower Urinary Tract
T2 Smith & Tanagho's General Urology, 19e
YR 2020
FD 2020
PB McGraw Hill
PP New York, NY
SN 9781259834332
LK accesssurgery.mhmedical.com/content.aspx?aid=1171184633
RD 2024/04/19
AB The  bladder,  in  concert  with  the  urethra  and  the  pelvic  floor,  is  responsible  for  storage  and  periodic  expulsion  of  urine.  The  integrated  function  of  these  components  of  the  lower  urinary  tract  (LUT)  is  dependent  on  a  complex  control  system  in  the  brain,  spinal  cord,  and  peripheral  ganglia,  and  on  local  regulatory  factors  (de  Groat  and  Yoshimura,  2001,  2006,  2015).  Dysfunction  of  the  central  nervous  control  systems  or  of  the  components  of  the  LUT  can  produce  voiding  difficulties  and  retention  of  urine,  or  different  types  of  urinary  incontinence  (mainly  urgency  and  stress  incontinence),  or  the  symptom  complex  of  the  “overactive  bladder”  (OAB),  characterized  by  urgency  and  frequency  with  or  without  urgency  incontinence,  often  with  nocturia  (Abrams  et  al,  2002).