RT Book, Section A1 McNamee, Ciaran J. A1 Hassan, Khalil A. A2 Sugarbaker, David J. A2 Bueno, Raphael A2 Burt, Bryan M. A2 Groth, Shawn S. A2 Loor, Gabriel A2 Wolf, Andrea S. A2 Williams, Marcia A2 Adams, Ann SR Print(0) ID 1170416532 T1 Resection of Benign Anterior and Middle Mediastinal Cysts and Tumors T2 Sugarbaker’s Adult Chest Surgery, 3e YR 2020 FD 2020 PB McGraw-Hill Education PP New York, NY SN 9781260026931 LK accesssurgery.mhmedical.com/content.aspx?aid=1170416532 RD 2024/04/20 AB Primary benign anterior and middle mediastinal tumors arise from mediastinal structures either as benign proliferative processes or as a consequence of inflammation. They may also occur as a result of the arrest of embryonic cells traversing this compartment with later tumor growth (germ cell tumors). The majority of benign mediastinal tumors are either cystic or solid; if solid they derive primarily from the thymus, or they extend downward from the superior mediastinum (thyroid substernal goiter), or to a lesser extent they derive from mediastinal mesenchymal tissue. Primary mesenchymal mediastinal tumors represent fewer than 10% of primary mediastinal tumors and have a higher prevalence for malignant potential in children.1