RT Book, Section A1 Mak, Raymond H. A1 Baldini, Elizabeth H. A2 Sugarbaker, David J. A2 Bueno, Raphael A2 Burt, Bryan M. A2 Groth, Shawn S. A2 Loor, Gabriel A2 Wolf, Andrea S. A2 Williams, Marcia A2 Adams, Ann SR Print(0) ID 1170411485 T1 Neoadjuvant and Adjuvant Radiotherapy for Non–Small-Cell Lung Cancer T2 Sugarbaker’s Adult Chest Surgery, 3e YR 2020 FD 2020 PB McGraw-Hill Education PP New York, NY SN 9781260026931 LK accesssurgery.mhmedical.com/content.aspx?aid=1170411485 RD 2024/04/24 AB Radiation therapy (RT) plays an important role in the management of locally advanced non–small-cell lung cancer (NSCLC). In the neoadjuvant (preoperative) setting, thoracic RT with concurrent chemotherapy (CT) can be an effective means for downstaging mediastinal disease and improving the likelihood of complete resection. In the adjuvant (postoperative) setting, RT may decrease the risk of locoregional recurrence for patients with high-risk disease such as pathologic N2 involvement and/or positive margins. Modern techniques of radiation treatment planning and delivery have improved the safety profile and efficacy of thoracic RT.