RT Book, Section A1 Gill, Ritu R. A1 Lapidot, Moshe A1 Bueno, Raphael A2 Sugarbaker, David J. A2 Bueno, Raphael A2 Burt, Bryan M. A2 Groth, Shawn S. A2 Loor, Gabriel A2 Wolf, Andrea S. A2 Williams, Marcia A2 Adams, Ann SR Print(0) ID 1170411019 T1 Image-Guided Video-Assisted Thoracoscopic Surgery (iVATS) for Early Lung Cancer T2 Sugarbaker’s Adult Chest Surgery, 3e YR 2020 FD 2020 PB McGraw-Hill Education PP New York, NY SN 9781260026931 LK accesssurgery.mhmedical.com/content.aspx?aid=1170411019 RD 2023/03/25 AB Lung cancer is associated with high morbidity and mortality. In 2018, the estimated number of new cases of lung cancer in the United States alone was 234,030 (121,680 in men and 112,350 in women), and the number of deaths was 154,050 (83,550 in men and 70,500 in women).1 The National Lung Screening Trial (NLST), launched in 2002, reported reduced lung-cancer mortality in patients undergoing low-dose computed tomographic (CT) screening.2 The trial enrolled more than 53,000 heavy smokers and reported 20% fewer lung cancer deaths among trial participants in the intervention group.2 However, the majority of nodules detected by CT were benign, requiring interval follow-up or biopsies for definitive diagnosis. As the NELSON trial recently reported, fewer than 1% of newly diagnosed subsolid nodules are malignant, and only 6% of participants with a new subsolid nodule have early lung cancer (adenocarcinoma in situ).3