RT Book, Section
A1 Chan, Yvonne
A1 Goddard, John C.
SR Print(0)
ID 1172372047
T1 Tumor Biology of Head and Neck Cancer
T2 K.J. Lee’s Essential Otolaryngology: Head and Neck Surgery, 12e
YR 2019
FD 2019
PB McGraw-Hill Education
PP New York, NY
SN 9781260122237
LK accesssurgery.mhmedical.com/content.aspx?aid=1172372047
RD 2024/04/25
AB Results  from  next-generation  sequencing  efforts,  as  well  as  gene  expression  analysis  has  made  it  obvious  that  this  information  will  be  critical  for  estimating  prognosis  and  determining  appropriate  therapy  for  head  and  neck  cancers.  The  Cancer  Genome  Atlas  (TCGA),  supported  by  the  National  Cancer  Institute  (NCI),  has  provided  detailed  information  about  common  gene  defects  and  expression  patterns,  as  well  as  protein  expression  profiles  found  in  head  and  neck  squamous  cell  carcinoma  (HNSCC).  Although  similar  data  are  emerging  for  some  salivary  cancer  types  and  molecular  analyses  of  thyroid  cancers  are  rapidly  evolving,  we  will  limit  discussion  here  to  HNSCC.