RT Book, Section
A1 Chan, Yvonne
A1 Goddard, John C.
SR Print(0)
ID 1172369427
T1 Congenital Hearing Loss
T2 K.J. Lee’s Essential Otolaryngology: Head and Neck Surgery, 12e
YR 2019
FD 2019
PB McGraw-Hill Education
PP New York, NY
SN 9781260122237
LK accesssurgery.mhmedical.com/content.aspx?aid=1172369427
RD 2024/09/15
AB Deafness  is  the  most  common  sensory  defect  (1  in  1000-2000  births;  there  are  roughly  4  million  births  in  the  United  States  per  year).Early  identification  allows  appropriate  intervention  as  soon  as  indicated.Fifty  percent  of  congenital  hearing  loss  is  due  to  nongenetic  factors.Environmental  (25%  of  all  congenital  hearing  loss  cases)Infections  (TORCH)OtotoxicityPrematurityExtracorporeal  membrane  oxygenation  (ECMO)HypoxiaIdiopathic  (25%  of  all  congenital  hearing  loss  cases)Fifty  percent  of  congenital  hearing  loss  is  due  to  genetic  factorsSeventy  percent  of  genetic  cases  are  nonsyndromicSeventy-five  percent  to  80%  of  nonsyndromic  deafness  is  inherited  through  autosomal  recessive  (AR)  patterns.Eighteen  percent  to  20%  of  nonsyndromic  deafness  is  inherited  through  autosomal  dominant  (AD)  patterns.One  percent  to  3%  of  nonsyndromic  deafness  is  classified  as  X-linked,  or  chromosomal  disorders.Thirty  percent  of  genetic  cases  are  syndromicThe  majority  of  these  cases  are  passed  on  through  AR  or  X-linked  inheritance.