RT Book, Section
A1 Bouwense, Stefan A.W.
A1 van Santvoort, Hjalmar C.
A1 Besselink, Marc G.H.
A2 Zinner, Michael J.
A2 Ashley, Stanley W.
A2 Hines, O. Joe
SR Print(0)
ID 1160045604
T1 Perspective on Management of Patients with Acute Pancreatitis
T2 Maingot's Abdominal Operations, 13e
YR 2019
FD 2019
PB McGraw-Hill Education
PP New York, NY
SN 9780071843072
LK accesssurgery.mhmedical.com/content.aspx?aid=1160045604
RD 2023/03/25
AB Acute  pancreatitis  is  the  most  common  gastrointestinal  disease  for  which  patients  are  acutely  hospitalized,  and  its  incidence  continues  to  rise.1  The  majority  of  patients  (approximately  80%)  with  acute  pancreatitis  have  mild  disease,  and  symptoms  usually  resolve  within  1  week  with  basic  supportive  care.2,3  The  other  20%  of  patients  develop  a  severe  form  of  pancreatitis  with  organ  failure  and  necrotizing  pancreatitis.  Necrotizing  pancreatitis  is  now  defined  as  either  pancreatic  parenchymal  necrosis  and  peripancreatic  fat  necrosis  or  peripancreatic  fat  necrosis  alone.2,4  The  clinical  course  of  these  patients  is  often  characterized  by  a  persisting  systemic  inflammatory  response  syndrome  and/or  (multiple)  organ  failure  for  the  first  1  to  2  weeks.  Despite  maximal  supportive  care  in  the  intensive  care  unit,  mortality  is  up  to  30%  in  patients  with  early  persisting  organ  failure.5,6  Secondary  infection  of  the  necrosis  develops  in  30%  of  patients  and  carries  a  mortality  risk  of  approximately  15%.7,8