RT Book, Section A1 Patel, Sameer H. A1 Passot, Guillaume A1 Vauthey, Jean-Nicolas A2 Zinner, Michael J. A2 Ashley, Stanley W. A2 Hines, O. Joe SR Print(0) ID 1160044288 T1 Malignant Liver Neoplasms T2 Maingot's Abdominal Operations, 13e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9780071843072 LK accesssurgery.mhmedical.com/content.aspx?aid=1160044288 RD 2024/04/19 AB In 2018, primary liver tumors will be diagnosed in approximately 42,220 new patients in the United States, and approximately 30,200 individuals will die from this disease.1 Worldwide, primary liver tumors remain the second leading cause of death from cancer in males and the sixth leading cause of death from cancer in females.2 Malignant lesions can arise from any of the various cell types that comprise the organ, which include hepatocytes, endothelial cells, and the cells of the intrahepatic bile ducts. The 2 most common hepatic neoplasms are hepatocellular carcinoma (HCC), which accounts for more than 75% of primary liver tumors, and intrahepatic cholangiocarcinoma (ICC), which accounts for 10% to 15%. The remaining primary hepatic neoplasms are hepatic angiosarcoma, epithelioid hemangioendothelioma, and hepatic lymphoma. The focus of this chapter will be on HCC and ICC.