RT Book, Section A1 Hunter, John G. A1 Spight, Donn H. A1 Sandone, Corinne A1 Fairman, Jennifer E. SR Print(0) ID 1162530145 T1 Total (Nissen) Fundoplication T2 Atlas of Minimally Invasive Surgical Operations YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9780071449052 LK accesssurgery.mhmedical.com/content.aspx?aid=1162530145 RD 2023/10/01 AB Laparoscopic total or Nissen fundoplication is indicated for individuals with gastroesophageal reflux disease (GERD) that meets one of the following criteria: (1) GERD that is refractory to proton pump inhibition, (2) GERD that is incompletely responsive to proton pump inhibition, (3) GERD that is entirely responsive to proton pump inhibition, but patient choice or side effect profile merits consideration of antireflux surgery, (4) extraesophageal manifestations of GERD, and (5) complications of GERD (stricture, bleeding, aspiration, Barrett esophagus). Of these criteria, the patients who are most likely to achieve complete symptom relief are those who are responsive to medical therapy, who have esophageal symptoms of reflux (heartburn, regurgitation, chest pain), and those with a strongly positive pH study (see later discussion).