RT Book, Section A1 Saltz, Leonard B. A2 Morita, Shane Y. A2 Balch, Charles M. A2 Klimberg, V. Suzanne A2 Pawlik, Timothy M. A2 Posner, Mitchell C. A2 Tanabe, Kenneth K. SR Print(0) ID 1145762620 T1 Adjuvant Therapy and Treatment of Systemic Disease for Colon Cancer T2 Textbook of Complex General Surgical Oncology YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9780071793315 LK accesssurgery.mhmedical.com/content.aspx?aid=1145762620 RD 2024/10/03 AB In 2014 an estimated 96,830 new cases of colon cancer were diagnosed in the United States alone (National Cancer Institute: http://www.cancer.gov/types/colorectal). In developed countries, colon cancer is two to three times more common than rectal cancer, while in rural Asia and Africa the incidence is reversed. Interestingly, as diets Westernize in Asian cities, both the incidence of colorectal cancer in general and the relative incidence of colon versus rectal cancer in particular increase. Epidemiologic studies indicate a rising proportion of right-sided tumors in developed countries as well. This, too, is likely due to factors associated with diet and, possibly, environment. This chapter reviews the most current information on the systemic treatment of colon cancer.