RT Book, Section A1 Ferro, Adam A1 Zellars, Richard A2 Morita, Shane Y. A2 Balch, Charles M. A2 Klimberg, V. Suzanne A2 Pawlik, Timothy M. A2 Posner, Mitchell C. A2 Tanabe, Kenneth K. SR Print(0) ID 1145760765 T1 Radiation Therapy for High-Risk Breast Cancer T2 Textbook of Complex General Surgical Oncology YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9780071793315 LK accesssurgery.mhmedical.com/content.aspx?aid=1145760765 RD 2024/03/29 AB Radiotherapy is utilized as a part of breast-conserving therapy (lumpectomy followed by radiation therapy) or as an adjuvant therapy to mastectomy. This chapter focuses on recommendations for the use of adjuvant radiation therapy in the treatment of lymph node positive and high-risk lymph node negative breast cancer. Lower-risk disease will be covered in other chapters. Adjuvant radiation therapy recommendations for patients with node-positive disease are equally applicable in both mastectomy and breast-conserving therapy patients in most cases. Thus, the following recommendations for postmastectomy radiation therapy can be used interchangeably with patients treated with breast-conserving therapy. Controversial management decisions in the setting of one to three positive nodes, neoadjuvant chemotherapy, positive/close mastectomy margins, and T3N0 primary tumors will be covered in this chapter.