RT Book, Section
A1 Flanagan, Meghan
A1 Chen, Yunn-Yi
A1 Hwang, E. Shelley
A2 Morita, Shane Y.
A2 Balch, Charles M.
A2 Klimberg, V. Suzanne
A2 Pawlik, Timothy M.
A2 Posner, Mitchell C.
A2 Tanabe, Kenneth K.
SR Print(0)
ID 1145760168
T1 Ductal Carcinoma in Situ
T2 Textbook of Complex General Surgical Oncology
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9780071793315
LK accesssurgery.mhmedical.com/content.aspx?aid=1145760168
RD 2024/04/16
AB Ductal  carcinoma  in  situ  (DCIS)  is  a  preinvasive  clinical  diagnosis  that  lies  in  the  continuum  between  epithelial  atypia  and  invasive  cancer.  Although  it  has  been  recognized  and  treated  for  almost  three  decades,  much  remains  controversial  about  this  disease  and  its  optimal  treatment.  The  incidence  of  DCIS  has  increased  significantly  since  it  was  first  described,  largely  as  a  consequence  of  widespread  mammographic  screening.  Accordingly  the  presentation  pattern  has  changed  from  a  predominantly  palpable  lesion  to  one  whose  first  indication  is  that  of  an  incidentally  discovered  mammographic  abnormality  on  routine  screening  examination.  Because  DCIS  is  a  preinvasive  condition  with  heterogenous  potential  for  invasion,  there  remains  ongoing  debate  over  whether  the  current  treatment  recommendations  represent  overtreatment  of  some  DCIS  which  may  have  never  resulted  in  clinical  consequences  during  a  patient’s  lifetime.  This  chapter  reviews  the  epidemiology,  diagnosis,  and  treatment  of  DCIS  as  well  as  some  future  directions  for  clinical  management  of  the  disease.