RT Book, Section
A1 King, Tari A.
A1 Reis-Filho, Jorge S.
A2 Morita, Shane Y.
A2 Balch, Charles M.
A2 Klimberg, V. Suzanne
A2 Pawlik, Timothy M.
A2 Posner, Mitchell C.
A2 Tanabe, Kenneth K.
SR Print(0)
ID 1145760105
T1 Lobular Carcinoma in Situ and Lobular Neoplasia
T2 Textbook of Complex General Surgical Oncology
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9780071793315
LK accesssurgery.mhmedical.com/content.aspx?aid=1145760105
RD 2024/04/24
AB The  term  lobular  neoplasia  (LN)  encompasses  the  entire  spectrum  of  atypical  epithelial  lesions  that  originate  in  the  terminal  duct-lobular  unit  (TDLU)  of  the  breast,  and  are  characterized  by  a  population  of  dyshesive  cells,  which  expand  the  lobules  and  acini  of  the  TDLUs,  and  may  involve  the  terminal  ducts  in  a  pattern  known  as  Pagetoid  spread.1  These  lesions  were  traditionally  described  under  the  terms  lobular  carcinoma  in  situ  (LCIS)  and  atypical  lobular  hyperplasia  (ALH),  which  refer  to  the  degree  of  involvement  of  the  acinar  structures  of  a  given  TDLU.