RT Book, Section A1 Melotek, James A1 Unger, Keith A1 Gutfeld, Orit A1 Lee, Nancy A2 Morita, Shane Y. A2 Balch, Charles M. A2 Klimberg, V. Suzanne A2 Pawlik, Timothy M. A2 Posner, Mitchell C. A2 Tanabe, Kenneth K. SR Print(0) ID 1145758756 T1 Nasopharyngeal Cancer T2 Textbook of Complex General Surgical Oncology YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9780071793315 LK accesssurgery.mhmedical.com/content.aspx?aid=1145758756 RD 2024/04/25 AB The nasopharynx is the anatomical region bounded by the sphenoid bone superiorly, the soft palate inferiorly, the clivus and uppermost cervical vertebrae posteriorly, and the nasal choanae anteriorly. The lateral walls include the mucosa covering the torus tubarius, which forms the eustachian tube orifice, and the fossa of Rosenmüller, a recess that lies posterior to the torus. The eustachian tube pierces the pharyngobasilar fascia at the sinus of Morgagni, a common site for tumor infiltration. The American Joint Committee on Cancer (AJCC) defines three anatomic spaces that are in close proximity to the nasopharynx and are relevant for staging of nasopharyngeal carcinoma (NPC): the parapharyngeal space, the carotid space, and the masticator space.1 The parapharyngeal space lies lateral and posterior to the nasopharynx. It extends from the skull base down to the level of the angle of the mandible, and is anterior to the styloid process and medial to the masticator space. The carotid space is an enclosed fascial space that lies posterior to the styloid process and contains the internal carotid artery, internal jugular vein, and cranial nerves IX–XII. The masticator space includes the muscles of mastication and is enclosed by the superficial layer of the deep cervical fascia.