RT Book, Section
A1 Mallidi, Hari R.
A1 Anand, Jatin
A1 Robbins, Robert C.
A2 Cohn, Lawrence H.
A2 Adams, David H.
SR Print(0)
ID 1144168471
T1 Lung Transplantation and Heart-lung Transplantation
T2 Cardiac Surgery in the Adult, 5e
YR 2017
FD 2017
PB McGraw-Hill Education
PP New York, NY
SN 9780071844871
LK accesssurgery.mhmedical.com/content.aspx?aid=1144168471
RD 2024/10/15
AB Human  lung  transplantation,  performed  as  a  single  lung,  double  lung,  or  heart-lung  bloc,  has  emerged  as  a  life-saving  procedure  for  patients  with  end-stage  pulmonary  disease.  With  improvement  of  operative  techniques,  organ  preservation,  and  immunosuppressive  regimens,  combined  heart-lung  and  isolated  lung  transplantation  have  become  common  treatments  for  patients  with  a  variety  of  end-stage  disease  entities.  To  date,  3703  combined  heart-lung  transplants  and  43,428  lung  transplants  have  been  reported  worldwide.1  Although  the  number  of  heart-lung  transplants  performed  annually  has  declined  in  recent  years,  the  number  of  single-lung  transplantation  (SLT)  procedures  remains  stable,  accompanied  by  a  steady  increase  in  bilateral  lung  transplant  procedures  (Fig.  61-1).  Clinical  progress  in  thoracic  organ  transplantation  has  been  considerable,  yet  significant  barriers  that  limit  the  scope  of  these  procedures  still  remain.  These  include  donor  organ  shortage,  limited  preservation  techniques,  graft  rejection,  and  infectious  complications.  This  chapter  summarizes  the  state  of  the  art  in  combined  heart-lung  and  isolated  lung  transplantation.